The journal Interdisciplinary Social Research is an academic journals online that aims to provide dissemination of original research papers and reviews of related existing literature that emphasizes the complex interactions between different branches of social sciences. In this regard, the journal aims to enhance unique perspectives from professionals of various disciplines to address emerging multifaceted issues that affect global societies.
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Orthobiologics are an innovative area of development in musculoskeletal medicine that provides regenerative options as substitutes for conventional orthopedic procedures aimed at preserving joints and healing soft tissues. The purpose of this review was to critically assess orthobiologic therapy effectiveness, describe novel developments, and provide clinical and investigative recommendations. A systematic search of scholarly databases was conducted, targeting studies published from 2018 to 2025. 11 peer-reviewed articles were included and analyzed through thematic synthesis. Findings indicated that PRP, BMAC, and MSCs provide clinically relevant benefits of pain, function, and tissue repair in osteoarthritis and tendinopathy. Orthobiologics, exosome therapies, scaffold-enhanced delivery systems, and gene-activated matrices are newer innovations that are continuing to expand the clinical use of orthobiologics.
Orthopedics, Orthobiologics, Joint Preservation, Tissue Regeneration, Biotherapies